Therapeutic drug monitoring of atypical antipsychotics.

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Therapeutic drug monitoring of atypical antipsychotic drugs.

Schizophrenia is a severe psychiatric disorder often associated with cognitive impairment and affective, mainly depressive, symptoms. Antipsychotic medication is the primary intervention for stabilization of acute psychotic episodes and prevention of recurrences and relapses in patients with schizophrenia. Typical antipsychotics, the older class of antipsychotic agents, are currently used much ...

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Immunosuppressants require therapeutic drug monitoring because of their narrow therapeutic index and significant inter-individual variability in blood concentrations. This variability can be because of factors like drug-nutrient interactions, drug-disease interactions, renal-insufficiency, inflammation and infection, gender, age, polymorphism and liver mass. Drug monitoring is widely practiced ...

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Atypical antipsychotics in psychiatric practice: practical implications for clinical monitoring.

OBJECTIVES To provide practical recommendations for monitoring patients both before and during treatment with atypical antipsychotics, to assist clinicians in implementing preventative measures against diabetes, and to establish baselines according to which clinicians should initiate diabetes treatment. METHOD A working group of Canadian specialists in psychiatry and endocrinology reviewed pe...

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Prevalence of Therapeutic Drug Monitoring for Antidepressants and Antipsychotics in Stockholm, Sweden: A Longitudinal Analysis

BACKGROUND Although therapeutic drug monitoring (TDM) is considered an underused tool in psychiatric care, the prevalence of TDM is largely unknown. The aim of this study was to analyze the prevalence of TDM for antidepressants and antipsychotics during 2006-2013. METHODS The study population consisted of individuals ≥5 years of age residing in Stockholm County. The prevalence of TDM for each...

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ژورنال

عنوان ژورنال: Psychiatria Polska

سال: 2017

ISSN: 0033-2674,2391-5854

DOI: 10.12740/pp/65307